Install SIP: ============ Download http://sourceforge.net/projects/pyqt/files/sip/sip-4.17/sip-4.17.tar.gz Unpack python configure.py make make install Install PyQT: ============= Download http://sourceforge.net/projects/pyqt/files/PyQt5/PyQt-5.5.1/PyQt-gpl-5.5.1.tar.gz Unpack python configure.py --qmake /Users/michael/Applications/Qt/5.6/clang_64/bin/qmake make make install